Endoscopic Submucosal Dissection Market

Endoscopic Submucosal Dissection Market Size, Share 2024-2032

The endoscopic submucosal dissection (ESD) market is undergoing significant growth, with a valuation of USD 324.7 million in 2023. Projected to expand at a compound annual growth rate (CAGR) of 7.0% from 2024 to 2032, the market is anticipated to reach USD 594.5 million by the end of the forecast period. This growth is primarily driven by the rising incidence of gastrointestinal cancers worldwide.

Market Dynamics

Increasing Prevalence of Gastrointestinal Cancers

Gastrointestinal cancers, including gastric, esophageal, and colorectal cancers, are becoming increasingly prevalent. This rise in cancer cases has led to a greater demand for ESD procedures, which are minimally invasive and highly effective in treating early-stage cancers. ESD allows for the precise removal of cancerous lesions, reducing the need for more invasive surgeries.

Technological Advancements

The ESD market has witnessed significant technological advancements in recent years. Innovations in endoscopic devices and techniques have improved the precision, safety, and effectiveness of ESD procedures. For instance, the development of high-definition endoscopes and specialized ESD knives has enhanced the ability of physicians to accurately target and remove lesions.

Growing Awareness

There is a growing awareness among the public and healthcare professionals about the benefits of early cancer detection and treatment. Early-stage cancers are often treatable with minimally invasive procedures like ESD, leading to better patient outcomes and reduced healthcare costs. This increased awareness has resulted in more people opting for endoscopic screenings and treatments.

Reimbursement Policies

Favorable reimbursement policies in several countries have made ESD procedures more accessible and affordable for patients. Insurance coverage for ESD has encouraged more individuals to undergo these procedures, contributing to the growth of the market.

External Trends

Shift Towards Minimally Invasive Procedures

There is a global trend towards preferring minimally invasive surgeries over traditional open surgeries. ESD is a prime example of this shift, offering benefits such as reduced hospital stays, quicker recovery times, and lower risks of complications. This trend is expected to continue, further driving the growth of the ESD market.

Integration of AI and Robotics

The integration of artificial intelligence (AI) and robotics into endoscopic procedures is revolutionizing the ESD market. AI-powered systems can assist physicians in identifying lesions more accurately, while robotic platforms can enhance the precision of the ESD procedure. These technological advancements are expected to improve patient outcomes and expand the applications of ESD.

Expansion of Applications

While ESD was initially developed for treating gastrointestinal cancers, its applications are expanding to include other areas such as early-stage lung and esophageal cancers. Research is ongoing to explore the potential of ESD in treating a wider range of conditions, further broadening the market.

Market Segmentation


The ESD market can be segmented based on the application, including:

  • Gastric ESD: Removal of lesions from the stomach.
  • Esophageal ESD: Treatment of early-stage esophageal cancer and precancerous lesions.
  • Colorectal ESD: Removal of lesions from the colon and rectum.
  • Others: This includes applications in the treatment of lung and duodenal cancers.

End User

The market can also be segmented based on end users, such as:

  • Hospitals: The largest segment, where most ESD procedures are performed.
  • Ambulatory Surgical Centers: These centers offer a cost-effective alternative to hospitals for outpatient ESD procedures.
  • Specialized Clinics: Clinics that specialize in endoscopic procedures, including ESD.


Geographically, the market is segmented into:

  • North America: A major market for ESD, driven by advanced healthcare infrastructure and high awareness.
  • Europe: Strong growth is expected due to increasing healthcare expenditure and technological advancements.
  • Asia-Pacific: The fastest-growing region, due to the rising prevalence of gastrointestinal cancers and improving healthcare facilities.
  • Latin America and the Middle East & Africa: These regions are expected to witness gradual growth, driven by improving healthcare infrastructure and increasing awareness.

Recent Developments

Technological Innovations

The ESD market has seen the introduction of new devices and accessories that enhance the efficiency and safety of the procedure. For example, the development of traction devices helps in providing a clearer view of the lesion, while specialized ESD knives improve the precision of the dissection.

Clinical Trials

Ongoing clinical trials are focused on evaluating the efficacy of ESD in various applications, including the treatment of early-stage lung and esophageal cancers. These trials aim to refine the ESD technique for better outcomes and expand its applications.

Collaborations and Partnerships

Companies and research institutions are increasingly collaborating to develop advanced endoscopic technologies and expand the applications of ESD. These partnerships are crucial for driving innovation and bringing new products to the market.

Key Players

Prominent players in the ESD market include:

  • Olympus Corporation: A leading manufacturer of endoscopic devices, including ESD knives and high-definition endoscopes.
  • Fujifilm Holdings Corporation: Known for its innovative endoscopic imaging technologies and accessories.
  • Boston Scientific Corporation: Offers a range of endoscopic devices and is actively involved in research and development.
  • CONMED Corporation: Specializes in surgical and endoscopic technologies, including ESD equipment.
  • Ethicon (Johnson & Johnson): Provides advanced surgical instruments and devices, including those used in ESD procedures.

These companies are continuously investing in research and development to enhance their product offerings and maintain their competitive edge in the market.


Q1: Is ESD suitable for all types of gastrointestinal cancers? A1: ESD is most suitable for early-stage cancers and precancerous lesions that have not spread to deeper layers of the gastrointestinal tract. It may not be appropriate for advanced cancers that have invaded deeper tissues.

Q2: What are the risks associated with ESD? A2: While ESD is generally safe, there are some risks, including bleeding, perforation of the gastrointestinal wall, and infection. However, these complications are rare and can be managed effectively.

Q3: How long does recovery take after an ESD procedure? A3: Recovery time varies depending on the individual and the extent of the procedure. Typically, patients can resume normal activities within a few days, but they may need to follow a special diet and avoid strenuous activities for a short period.

Q4: How does ESD compare to traditional surgery? A4: ESD is less invasive than traditional surgery, offering advantages such as shorter hospital stays, quicker recovery, and lower risks of complications. It also allows for the precise removal of lesions, preserving healthy tissue.

Q5: Are ESD procedures covered by insurance? A5: Coverage for ESD procedures varies depending on the insurance provider and the specific policy. In many cases, ESD is covered as a treatment for early-stage gastrointestinal cancers, but patients should check with their insurance provider for details.

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